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A 63 yr old female has been transferred to your hospital following a motor-vehicle accident in which the car she was driving rolled off the highway at 90 km/hr. At the scene she had a GCS 3/15 and multiple facial injuries. She was intubated and on arrival is paralysed and sedated, with heart rate 110 bpm, blood pressure 110/60 mmHg, SpO2 99% on FiO2 60%.

Answer the following questions


  • Question 1
  • Question 2
  • Question 3
  • Question 4
  • Question 5

Describe the abnormalities on this CT scan

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Briefly list your initial management priorities in this patient

On day 3 patient has persistent intracranial hypertension. Urine output has been 200 ml/hr for the last 4 hours. Describe the biochemistry attached. What is the most likely aetiology? How will you manage the polyuria?

Blood
Sodium 148 mmol/L
Potassium 4.0 mmol/L
Chloride 115 mmol/L
Bicarbonate 23 mmol/L
Glucose 6.0 mmol/L
Urea 8.0 mmol/L
Creatinine 75 umol/L
Osmolality 320 mmol/kg

Urine
Sodium 80 mmol/L
Osmolality 340 mmol/kg

On assessment patient has fixed, dilated pupils, is not breathing, and has no response to painful stimulus. Patient has been on morphine and midazolam at high dose since admission. You are asked to establish clinically if brain death is present. What are the requirements to clinically establish brain death?

Clinical testing is unable to be performed due to the presence of medications and facial trauma. What other methods are available to fulfill brain death criteria? What investigations are shown below? Describe the findings.

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